| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 10940992 | Immunobiology | 2015 | 15 Pages |
Abstract
This review summarizes the physiological and pathophysiological aspects of macrophage iron metabolism and highlights its relevant consequences on immune function and in common diseases such as infection and atherosclerosis.
Keywords
NF-κBLPSTransferrinMYD88BAINrf2ERKMDSRBCABCA1TNFR1EAETLRERRARG1TGFDMT1ACDHeme oxygenase-1HIFPDGFDHBANOS2IRPHMOX1CD163SLC11A1IRETfR1LXRNRAMP1LCN2T helperFpn1FlvcrTIMABCG5IL-4RαBACH1Interferon-gamma receptorHpxNF-IL6Hcp1CD91TNF receptor-1TNFSCARA5IFNγRKeapMer tyrosine kinaseUTRJanus kinaseMAPKROSTRIFArginase-1STATexperimental autoimmune encephalomyelitisIronapoapolipoproteinNutritional immunityinterferonIFNinterleukinTAMtransforming growth factorTRAMtoll like receptorTumor associated macrophageSPIONdihydroxybenzoic acidMERTKDendritic cellendoplasmatic reticulummyelodysplastic syndromemononuclear phagocyte systemInfectionplatelet-derived growth factorHypoxia Inducible Factortumor necrosis factorNuclear factor-kappa BFerritinLactoferrinlow density lipoproteinsLDLlipopolysaccharidelipocalin-2MacrophageSignal transducer and activator of transcriptionMHCmajor histocompatibility complexuntranslated regioncarbon monoxideTRIF-related adaptor moleculemitogen activated kinaseSuperparamagnetic iron oxide nanoparticleMPsNitric oxideHaptoglobinHemopexinHemoglobinmyeloid differentiation primary response gene 88iron regulatory proteinJAKliver X receptorAnemia of chronic diseaseAnemia of inflammationred blood cellReactive oxygen speciesestrogen-related receptortransferrin receptor-1
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Authors
Manfred Nairz, Andrea Schroll, Egon Demetz, Ivan Tancevski, Igor Theurl, Günter Weiss,