| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 10953750 | Journal of Molecular and Cellular Cardiology | 2012 | 10 Pages |
Abstract
⺠Myofibroblasts/osteoblasts transdifferentiation correlated positively with PF in situ. ⺠PICs display a marked phenotypic plasticity under appropriate microenvironment. ⺠PICs spontaneously transdifferentiate into myofibroblasts/osteoblasts when grown in vitro. ⺠PICs exhibit a more limited self-renewal capacity and undergo earlier senescence than MSCs. ⺠Oct4 and Klf4 are important self-renewal-related genes of PICs.
Related Topics
Life Sciences
Biochemistry, Genetics and Molecular Biology
Cell Biology
Authors
Xiaohong Liu, Mengwei Tan, Dejun Gong, Lin Han, Fanglin Lu, Shengdong Huang, Zhiyun Xu,