Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
10953755 | Journal of Molecular and Cellular Cardiology | 2012 | 9 Pages |
Abstract
⺠We examined functional effects of endothelial-derived OSCAR by proteomics. ⺠Regulated proteins are involved in cell-to-cell signaling and inflammatory response. ⺠STAT1 and STAT3 are reciprocally activated by OSCAR. ⺠OSCAR affects adhesion proteins and increases monocyte adhesion. ⺠The study indicates a novel role of OSCAR in the vascular-immune cross-talk.
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Authors
Claudia Goettsch, Stefanie Kliemt, Kathrin Sinningen, Martin von Bergen, Lorenz C. Hofbauer, Stefan Kalkhof,