Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
10953774 | Journal of Molecular and Cellular Cardiology | 2012 | 9 Pages |
Abstract
⺠In this study we studied mechanisms of oxLDL-upregulated miR-29b. ⺠OxLDL activated miR-29b from microRNA-29b-1/microRNA-29a cluster gene. ⺠The LOX-1/Ca2+/ROS/ERK/c-Fos involved in oxLDL-mediated miR-29b overexpression. ⺠OxLDL-downregulated HDAC1 affected miR-29b expression. ⺠OxLDL-mediated histone 3 lysine 4 (H3K4) and H3K9 regulated miR-29b expression.
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Authors
Ku-Chung Chen, Yi-Chu Liao, I-Chung Hsieh, Yung-Song Wang, Ching-Yu Hu, Suh-Hang Hank Juo,