| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 10953787 | Journal of Molecular and Cellular Cardiology | 2012 | 9 Pages |
Abstract
⺠Eya2 directly regulates the expression of mTOR during physiological hypertrophy. ⺠Eya2 and Six1 synergistically up-regulate mTOR expression. ⺠Eya2 TG exhibits characteristics of physiological cardiac hypertrophy. ⺠Mitochondrial integrity is preserved in Eya2 TG hearts under pressure overload. ⺠Activation of Eya2 and Six1 transcriptional complex is cardioprotective.
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Authors
Seung Hee Lee, Jooyeon Kim, Joo Young Ryu, Suho Lee, Dong Kwon Yang, Dongtak Jeong, Jaetaek Kim, Sang-Hee Lee, Jin Man Kim, Roger J. Hajjar, Woo Jin Park,