| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 10953790 | Journal of Molecular and Cellular Cardiology | 2012 | 12 Pages |
Abstract
⺠AE3 Clâ/HCO3â- exchanger interacts with the CAXIV enzyme in the heart. ⺠CAXIV bound to and raised AE3 transport, establishing a physical/functional complex. ⺠Hypertrophic rat hearts showed elevated CAXIV protein expression. ⺠AE-mediated HCO3â fluxes increased in the hypertrophic myocardium compared to normal. ⺠AE3/CAXIV complex formation would render AE3 hyperactive in the hypertrophic heart.
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Authors
Lorena A. Vargas, Bernardo V. Alvarez,