Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
10953797 | Journal of Molecular and Cellular Cardiology | 2012 | 13 Pages |
Abstract
⺠The pathogenesis of doxorubicin-induced cardiotoxicity is complex and multifactorial. ⺠Oxidative stress is a major cause of doxorubicin-induced cardiotoxicity. ⺠Doxorubicin-induced heart failure can appear very late after the last administration. ⺠There is no specific curative or preventive treatment available.
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Authors
Yanti Octavia, Carlo G. Tocchetti, Kathleen L. Gabrielson, Stefan Janssens, Harry J. Crijns, An L. Moens,