Article ID Journal Published Year Pages File Type
10953815 Journal of Molecular and Cellular Cardiology 2012 11 Pages PDF
Abstract
► Ablation of calsequestrin accelerates restitution of Ca2+ release from SR. ► The ablation of calsequestrin speeds up the rate of change of Ca2+ within the SR. ► The lack of calsequestrin does not affect the restitution Ca2+ influx through the plasma membrane. ► Calsequestrin regulates the appearance of Ca2+ alternans and AP repolarization alternans. ► Calsequestrin ablation modifies TW-alternans.
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