Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
10953815 | Journal of Molecular and Cellular Cardiology | 2012 | 11 Pages |
Abstract
⺠Ablation of calsequestrin accelerates restitution of Ca2+ release from SR. ⺠The ablation of calsequestrin speeds up the rate of change of Ca2+ within the SR. ⺠The lack of calsequestrin does not affect the restitution Ca2+ influx through the plasma membrane. ⺠Calsequestrin regulates the appearance of Ca2+ alternans and AP repolarization alternans. ⺠Calsequestrin ablation modifies TW-alternans.
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Authors
Dmytro Kornyeyev, Azade D. Petrosky, Bernardo Zepeda, Marcela Ferreiro, Bjorn Knollmann, Ariel L. Escobar,