| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 10953816 | Journal of Molecular and Cellular Cardiology | 2012 | 11 Pages |
Abstract
⺠We compare Ca2+ transients in ventricular myocytes from female mice with and without ovaries. ⺠Ovariectomy increases internal Ca2+ stores and Ca2+ release without affecting Ca2+ current. ⺠Ovariectomy increases Ca2+ spark size and frequency, without affecting spark width or duration. ⺠Sex steroid hormones may modulate unitary Ca2+ release in individual cardiac myocytes.
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Authors
Elias Fares, Randi J. Parks, Jennifer K. MacDonald, Jeanne M.S. Egar, Susan E. Howlett,