| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 10953836 | Journal of Molecular and Cellular Cardiology | 2012 | 8 Pages |
Abstract
⺠Bone morphogenic protein 4 (BMP4) induces endothelial cell apoptosis. ⺠BMP4 increases cleaved caspase-3 activation. ⺠BMP4 activates BMPR1A and NOX4, leading to ROS production. ⺠Inhibition of JNK signaling blunts BMP4-induced endothelial cell apoptosis.
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Authors
Xiao Yu Tian, Lai Hang Yung, Wing Tak Wong, Jian Liu, Fung Ping Leung, Limei Liu, Yangchao Chen, Siu Kai Kong, Kin Ming Kwan, Siu Man Ng, Paul B.S. Lai, Lai Ming Yung, Xiaoqiang Yao, Yu Huang,