| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 10953852 | Journal of Molecular and Cellular Cardiology | 2011 | 9 Pages |
Abstract
⺠ENTPDase-1 over expression protects the myocardium from ischemia-reperfusion injury. ⺠ENTPDase-1 mediated cardiac protection involves signaling through the adenosine A2B receptors. ⺠ENTPDase-1-mediated cardiac protection involves AKT and ERK1/2 activation. ⺠ENTPDase-1-mediated cardiac protection involves GSK-3β inactivation.
Keywords
8-SPTAMP2-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-onePD98059ADPCD39GSK-3βCD73MPTPERK 1/2DPCPX8-Cyclopentyl-1,3-dipropylxanthineAdenosine TriphosphateATPadenosine diphosphateMyocardial infarctionAktmitochondrial permeability transition poreEcto-5′-nucleotidaseMyocardial ischemiaReperfusionwild-typeSerine/threonine protein kinaseextracellular signal-regulated kinase 1/2Glycogen synthase kinase-3βAdenosine receptor
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Authors
Ming Cai, Zachary M. Huttinger, Heng He, Weizhi Zhang, Feng Li, Lauren A. Goodman, Debra G. Wheeler, Lawrence J. Druhan, Jay L. Zweier, Karen M. Dwyer, Guanglong He, Anthony J.F. d'Apice, Simon C. Robson, Peter J. Cowan, Richard J. Gumina,