| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 10953874 | Journal of Molecular and Cellular Cardiology | 2012 | 7 Pages |
Abstract
⺠The protective and deleterious effects of carbon monoxide (CO) in the myocardium are considered. ⺠Endogenous CO is clearly protective against ischemia/reperfusion injury. ⺠Protective effects of CO likely involve multiple second messenger pathways and ion channels. ⺠At higher concentrations, CO is cardiotoxic and pro-arrhythmic. ⺠The pro-arrhythmic effects of CO are likely to involve regulation of alternative ion channels.
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Authors
Chris Peers, Derek S. Steele,