Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
10953888 | Journal of Molecular and Cellular Cardiology | 2012 | 9 Pages |
Abstract
⺠We show that 5-HT2A receptors/caveolin-3 interaction increases upon agonist exposure. ⺠5-HT2A receptors stimulated with 5-HT traffic into caveolae microdomains. ⺠Caveolin-3 silencing enhances myocyte hypertrophy induced by 5-HT2A receptors. ⺠Caveolin-3 inhibits NFAT activation involved in 5-HT2A receptor-mediated hypertrophy.
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Authors
Jeanne Mialet-Perez, Romina D'Angelo, Christelle Villeneuve, Catherine Ordener, Anne Nègre-Salvayre, Angelo Parini, Cécile Vindis,