| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 10953889 | Journal of Molecular and Cellular Cardiology | 2012 | 8 Pages |
Abstract
⺠Failing hearts have a severely altered complement of PKA-AKAP signaling nodes. ⺠Altered PKA-AKAP signaling nodes explain several aspects of the failing phenotype. ⺠A chemical proteomics strategy reveals aberrant signaling at single AKAP resolution. ⺠Chemical proteomics identifies novel therapeutic targets for heart failure.
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Authors
Thin-Thin Aye, Siddarth Soni, Toon A.B. van Veen, Marcel A.G. van der Heyden, Salvatore Cappadona, Andras Varro, Roel A. de Weger, Nicolaas de Jonge, Marc A. Vos, Albert J.R. Heck, Arjen Scholten,