Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
10953906 | Journal of Molecular and Cellular Cardiology | 2012 | 9 Pages |
Abstract
⺠Experimental autoimmune myocarditis (EAM) is T cell-mediated disease. ⺠We have reported that fetal membrane (FM)-derived MSCs ameliorate EAM. ⺠We examine T cell differentiation in FM-MSC-administered EAM rats. ⺠FM-MSCs attenuate EAM via suppression of Th1 and Th17 immunity. ⺠Cultured FM-MSCs reduce Th1/Th17 cell-differentiation and proliferation.
Keywords
Related Topics
Life Sciences
Biochemistry, Genetics and Molecular Biology
Cell Biology
Authors
Makiko Ohshima, Kenichi Yamahara, Shin Ishikane, Kazuhiko Harada, Hidetoshi Tsuda, Kentaro Otani, Akihiko Taguchi, Mikiya Miyazato, Shinji Katsuragi, Jun Yoshimatsu, Makoto Kodama, Kenji Kangawa, Tomoaki Ikeda,