Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
10953915 | Journal of Molecular and Cellular Cardiology | 2012 | 9 Pages |
Abstract
⺠In virus myocarditis treatment with a CyPA-inhibitor affects lesion area and collagen. ⺠Macrophage, T cell infiltration and MMP9 expression were reduced by CyPA inhibition. ⺠Similar effects are found using CyPAâ/â mice in comparison to WT mice. ⺠CyPA may represent a target to modulate myocardial remodeling in myocarditis.
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Authors
Peter Seizer, Karin Klingel, Martina Sauter, Dirk Westermann, Carmen Ochmann, Tanja Schönberger, Rebecca Schleicher, Konstantinos Stellos, Eva-Maria Schmidt, Oliver Borst, Boris Bigalke, Reinhard Kandolf, Harald Langer, Meinrad Gawaz, Andreas E. May,