Article ID Journal Published Year Pages File Type
10953918 Journal of Molecular and Cellular Cardiology 2012 10 Pages PDF
Abstract
► PKA-phosphorylation of RyR2-S2808 is involved in Ca2+ release synchronization. ► RyR2-S2808 phosphorylation promotes Ca2+ wave acceleration. ► SR luminal Ca2+ sensing is reduced in unphosphorylatable RyR2-S2808A channels.
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Related Topics
Life Sciences Biochemistry, Genetics and Molecular Biology Cell Biology
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PKA phosphorylation of cardiac ryanodine receptor modulates SR luminal Ca2+ sensitivity
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