Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
10953920 | Journal of Molecular and Cellular Cardiology | 2012 | 11 Pages |
Abstract
âºPICOT increases cardiac contractility through inhibition of PKCζ activity. âºPICOT-mediated inhibition of PKCζ down-regulates PKCα activity. âºPICOT-mediated inhibition of PKCζ activity down-regulates PP2A activity. âºPICOT exerts significant functional benefits in failing hearts.
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Authors
Jae Gyun Oh, Dongtak Jeong, Hyeseon Cha, Ji Myoung Kim, Ekaterina Lifirsu, Jihwa Kim, Dong Kwon Yang, Chang Sik Park, Changwon Kho, Soonyong Park, Yung Joon Yoo, Do Han Kim, Jaetaek Kim, Roger J. Hajjar, Woo Jin Park,