| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 10953928 | Journal of Molecular and Cellular Cardiology | 2012 | 11 Pages |
Abstract
⺠We describe transient receptor potential vanilloid 2 (TRPV2) in the murine heart. ⺠We have identified a novel property of probenecid as a positive inotrope. ⺠Probenecid does not cause a positive inotropic response in TRPV2â/â mice. ⺠Probenecid increases myocyte cytosolic calcium concentration. ⺠Probenecid does not cause electrophysiologic changes in the murine heart or myocyte.
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Authors
Sheryl E. Koch, Xiaoqian Gao, Lauren Haar, Min Jiang, Valerie M. Lasko, Nathan Robbins, Wenfeng Cai, Cole Brokamp, Priyanka Varma, Michael Tranter, Yong Liu, Xiaoping Ren, John N. Lorenz, Hong-Sheng Wang, W. Keith Jones, Jack Rubinstein,