Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
10953960 | Journal of Molecular and Cellular Cardiology | 2011 | 8 Pages |
Abstract
⺠Adult stem cells for cardiac tissue engineering hold high clinical applicability. ⺠This strategy enhances cell retention and angiogenesis in the ischemic myocardium. ⺠Positive effects are due to paracrine mechanisms rather than cardiac differentiation. ⺠Only few clinical trials have tested ASC derived grafts for myocardial repair. ⺠Drawbacks related to graft's size and implantation risks still need to be addressed.
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Authors
Eliana C. Martinez, Theo Kofidis,