Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
10953993 | Journal of Molecular and Cellular Cardiology | 2010 | 7 Pages |
Abstract
⺠Ang II, binding to AT1 receptors, exerts an opposite effect on NBC isoforms. ⺠nNBC stimulation is mediated by ROS and ERK 1/2. ⺠p38 kinase mediates the Ang II-induced eNBC inhibition. ⺠nNBC stimulation may induce intracellular calcium overload. ⺠eNBC inhibition could lead to action potential prolongation.
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Authors
Verónica C. De Giusti, Alejandro Orlowski, Ernesto A. Aiello,