| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 10953995 | Journal of Molecular and Cellular Cardiology | 2010 | 7 Pages |
Abstract
âºPaclitaxel accelerates calcium oscillations in cardiomyocytes. âºPaclitaxel binds to neuronal calcium sensor 1 (NCS-1). âºNCS-1 enhances the activity of the InsP3R. âºThe extra InsP3R activity modulates the calcium oscillation frequency. âºThe effects of paclitataxel in cardiomyocytes is opposite that seen in neurons.
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Authors
Kun Zhang, Felix M. Heidrich, Brenda DeGray, Wolfgang Boehmerle, Barbara E. Ehrlich,