Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
10953996 | Journal of Molecular and Cellular Cardiology | 2010 | 5 Pages |
Abstract
⺠Fgf8 is required in Tbx1-expressing cells for heart development. ⺠Forced expression of Fgf8 in Tbx1 null embryos failed to rescue the heart phenotype. ⺠Fgf8, in the presence of low Tbx1 expression partially rescues the heart phenotype. ⺠Tbx1 null cells are unable to respond to Fgf8 in culture.
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Authors
Francesca Vitelli, Gabriella Lania, Tuong Huynh, Antonio Baldini,