| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 10954037 | Journal of Molecular and Cellular Cardiology | 2011 | 11 Pages |
Abstract
⺠The higher the expression of Cavβ2a in mice, the more Ca2+ influx and hypertrophy. ⺠Increased Ca2+ influx promotes hypertrophic response to TAC in mice. ⺠Cavβ2a expression induces cardiac myocyte hypertrophy in culture. ⺠Increased cytosolic Ca2+ activates calcineurin/NFAT pathway. ⺠SR-nuclear envelope Ca2+ release activates CaMK II/HDAC pathway.
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Authors
Xiongwen Chen, Hiroyuki Nakayama, Xiaoying Zhang, Xiaojie Ai, David M. Harris, Mingxin Tang, Hongyu Zhang, Christopher Szeto, Kathryn Stockbower, Remus M. Berretta, Andrea D. Eckhart, Walter J. Koch, Jeffery D. Molkentin, Steven R. Houser,