Article ID Journal Published Year Pages File Type
10954038 Journal of Molecular and Cellular Cardiology 2011 8 Pages PDF
Abstract
►PFTa blocks p53 activity and attenuates H2O2-induced cardiac apoptosis in vitro. ►PFTa significantly reduces the number of apoptotic cardiomyocytes after acute MI. ►Administration of PFTa increases infarct size and reduces 7-day survival rate. ►PFTa leads to adverse remodeling of infarct area after MI.
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Authors
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