Article ID Journal Published Year Pages File Type
10954039 Journal of Molecular and Cellular Cardiology 2011 8 Pages PDF
Abstract
► Disorganisation of the nuclear envelope and nesprin-1 in Lmna−/− cardiomyocytes. ► Enhanced osmotic stress responses suggest altered nuclear-cytoskeletal connections. ► Loss of lamin A/C is associated with heterogeneous distribution of nuclear G-actin. ► Nesprin-1 interacts with various cytoskeletal actin isoforms. ► Lmna−/− cardiomyocytes show increased cytoskeletal a-smooth muscle actin.
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