| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 10954043 | Journal of Molecular and Cellular Cardiology | 2011 | 12 Pages |
Abstract
⺠Ischemia activates the TLR-4-MyD88-dependent and -independent pathways in both ischemic and remote myocardium. ⺠Ischemia up-regulates TGF-β that gradually raises fibroblast detection and collagen fibrils. ⺠Reperfusion triggers apoptosis which progresses up to 6 days mainly in infiltrated macrophages. ⺠Reperfusion activates the Akt/mTOR/P70s6K mRNA translation and hypertrophy pathway
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Authors
Gemma Vilahur, Oriol Juan-Babot, Esther Peña, Blanca Oñate, Laura CasanÃ, Lina Badimon,