| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 10954046 | Journal of Molecular and Cellular Cardiology | 2011 | 9 Pages |
Abstract
âºHMR1098 has been considered a cardiac-specific KATP channel blocker. âºWe investigated chamber specificity of HMR action. âºAtrial (SUR1) channels are actually more sensitive than ventricular (SUR2A) channels. âºHMR is more effective on recombinant SUR1-based than SUR2A-based KATP channels. âºThe data have implications for use of HMR1098 to probe cardiac KATP.
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Authors
Hai Xia Zhang, Alejandro Akrouh, Harley T. Kurata, Maria Sara Remedi, Jennifer S. Lawton, Colin G. Nichols,