Article ID Journal Published Year Pages File Type
10954047 Journal of Molecular and Cellular Cardiology 2011 9 Pages PDF
Abstract
► An actively regulated disease process underlies pathological changes in AoVD. ► Interstitial cells in diseased AoV share traits of mesenchymal progenitor cells. ► Pediatric diseased AoVs do not calcify or express osteogenic genes. ► Osteogenic gene expression is evident in adult calcified diseased AoVs. ► Pediatric and adult diseased AoVs have shared progenitor gene expression.
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Life Sciences Biochemistry, Genetics and Molecular Biology Cell Biology
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