| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 10954069 | Journal of Molecular and Cellular Cardiology | 2011 | 8 Pages |
Abstract
⺠Pravastatin lowers resting heart rate (HR) in spontaneously hypertensive rats (SHR) ⺠Cardiac norepinephrine release & tachycardia are reduced by pravastatin in SHRs ⺠Neuronal NO signalling & NADPH oxidase expression are unchanged by pravastatin ⺠The effect of pravastatin on sympathetic neurotransmission is reversed by losartan. ⺠Pravastatin reduces cardiac angiotensin 2 & angiotensin converting enzymes 1 & 2
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Authors
Neil Herring, Chee Wan Lee, Nicholas Sunderland, Kathryn Wright, David J. Paterson,