| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 10954071 | Journal of Molecular and Cellular Cardiology | 2011 | 11 Pages |
Abstract
⺠CR improves LV diastolic function without affecting LV systolic function. CR attenuates the decline in SERCA2 protein and its activity. ⺠CR ameliorates age-related deterioration of Ca2+ handling during myocyte relaxation. ⺠CR suppresses the mTOR pathway and enhances autophagic flux in the heart.
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Authors
Ken Shinmura, Kayoko Tamaki, Motoaki Sano, Mitsushige Murata, Hiroyuki Yamakawa, Hideyuki Ishida, Keiichi Fukuda,