Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
10954074 | Journal of Molecular and Cellular Cardiology | 2011 | 10 Pages |
Abstract
âºLoss of interstitial collagen is a hallmark of volume overload (VO). âºAcute VO generates oxidative stress in rat left ventricle (LV). âºAcute VO results in LV subsarcolemmal mitochondrial (SSM) dysfunction. âºObserved degradation of SSM in acute VO is reversed by MMP inhibitor.
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Authors
Elena Ulasova, James D. Gladden, Yuanwen Chen, Junying Zheng, Betty Pat, Wayne Bradley, Pamela Powell, Jaroslaw W. Zmijewski, Blake R. Zelickson, Scott W. Ballinger, Victor Darley-Usmar, Louis J. Dell'Italia,