Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
10954079 | Journal of Molecular and Cellular Cardiology | 2011 | 9 Pages |
Abstract
⺠AV node provides the physiological delay between atrial and ventricular contraction. ⺠Presence of Cav1.3 Ca2+ channels in AV node in addition to Cav1.2. ⺠Cav1.3 plays an important role in AV node automaticity. ⺠Cav1.2 channel cannot functionally substitute for Cav1.3 channel in AV node. ⺠Identification of AV node-specific ion channels may provide a new therapeutic target.
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Authors
Qian Zhang, Valeriy Timofeyev, Hong Qiu, Ling Lu, Ning Li, Anil Singapuri, Cyril L. Torado, Hee-Sup Shin, Nipavan Chiamvimonvat,