| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 10954128 | Journal of Molecular and Cellular Cardiology | 2009 | 8 Pages |
Abstract
We designed an in vitro investigation to examine the role of MIP-1β on the development of atherosclerosis, including cell adhesion involving CAMs and ROS production, compared with angiotensin II. Furthermore, we investigated the prognostic impact of MIP-1β on stroke and cardiovascular events in hypertensive patients in a small cohort study.
Keywords
GTPMCP-1HUVECRac1ICAM-1ANGIILFA-1sVCAM-1VCAM-1LY294002VLA-4FBSsICAM-1MIP-1βDCFHDADPIPI3KVery late antigen 4CAMsECslymphocyte function-associated antigen 1Angiotensin IIinterleukincardiovascular diseasetumor necrosis factor-αDiphenyleneiodoniumCVDfetal bovine serumHuman umbilical vein endothelial cellsEndothelial cellsTNF-αmacrophage inflammatory protein-1βcell adhesion moleculesSoluble vascular cell adhesion molecule-1vascular cell adhesion molecule-1human immunodeficiency virusHIVMonocyte chemotactic protein-1Guanosine triphosphateReactive oxygen species
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Authors
Yuji Tatara, Mitsuru Ohishi, Koichi Yamamoto, Atsushi Shiota, Norihiro Hayashi, Yoshihiro Iwamoto, Masao Takeda, Takashi Takagi, Tomohiro Katsuya, Toshio Ogihara, Hiromi Rakugi,