Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
10954342 | Journal of Molecular and Cellular Cardiology | 2005 | 8 Pages |
Abstract
The prominent action of the P2Y11 receptor in controling cardiomyocyte contractility and possible alterations in its function during cardiomyopathy may suggest this receptor as a potential therapeutic target. It is possible that agonists for the P2Y11 receptor could be used to improve cardiac output in patients with circulatory shock and that P2Y11 receptor antagonist could be beneficial in patients with congestive heart failure (CHF).
Related Topics
Life Sciences
Biochemistry, Genetics and Molecular Biology
Cell Biology
Authors
Johanna Balogh, Anna-Karin Wihlborg, Henrik Isackson, Bhalchandra V. Joshi, Kenneth A. Jacobson, Anders Arner, David Erlinge,