Article ID Journal Published Year Pages File Type
10956204 Molecular and Cellular Endocrinology 2013 7 Pages PDF
Abstract
► TRH and PACAP increased prolactin promoter in PAC1R-transfected GH3 cells. ► The functions of TRHR and PAC1R changed after prolonged treatment with TRH and PACAP were examined. ► After long treatment with TRH/PACAP, prolactin promoter by TRH/PACAP were diminished. ► Prolonged pretreatment with both TRH and PACAP desensitized their own and each other's receptors.
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