Article ID Journal Published Year Pages File Type
10956207 Molecular and Cellular Endocrinology 2013 12 Pages PDF
Abstract
► We investigate a hypothesis that damaged germ cells induce inflammation in the testis. ► Damaged germ cell products induce inflammatory mediator up-regulation in Sertoli cells. ► TLR signaling pathways in the inflammatory mediator up-regulation were examined. ► Busulfan-induced germ cell damage induces an inflammatory milieu in the testis.
Keywords
Related Topics
Life Sciences Biochemistry, Genetics and Molecular Biology Cell Biology
Preview
Damaged spermatogenic cells induce inflammatory gene expression in mouse Sertoli cells through the activation of Toll-like receptors 2 and 4
Authors
, , , , , , , ,