| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 10956213 | Molecular and Cellular Endocrinology | 2013 | 8 Pages |
Abstract
⺠ANGPT1 was increased in FF and in granulosa-lutein cells from OHSS patients. ⺠Incubation of FF with an ANGPT1 inhibitor decreased endothelial cell migration. ⺠In the OHSS rat model, mTie-2 protein levels increased and PDGF-B and -D decreased. ⺠These results show a greater biological activity of ANGPTs/Tie-2 system in OHSS. ⺠PDGF-B and -D levels could be linked with the increased permeability in OHSS.
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Authors
Leopoldina Scotti, Dalhia Abramovich, Natalia Pascuali, Ignacio de Zúñiga, Alejandro Oubiña, Laura Kopcow, Soledad Lange, Gareth Owen, Marta Tesone, Fernanda Parborell,