| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 10956215 | Molecular and Cellular Endocrinology | 2013 | 8 Pages |
Abstract
⺠Expression of Lin28a and Lin28b decreases in the ovary prior to pubertal onset. ⺠Expression of Lin28a decreases in the hypothalamus prior to the onset of puberty. ⺠A decrease Lin28a protein levels mirrored the decline in Lin28a in ovarian tissue. ⺠Lin28 regulation of pubertal onset may occur at the ovarian and hypothalamic level. ⺠The effects of the Lin28 pathway may be mediated, in part, independently of Let-7.
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Authors
Anthony Grieco, Paulina Rzeczkowska, Christina Alm, Mark R. Palmert,