| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 10956216 | Molecular and Cellular Endocrinology | 2013 | 11 Pages |
Abstract
⺠Ecdysteroid receptor dsRNA injection led to a sustained decrease in EcR/RXR mRNAs. ⺠Knockdown disrupts blastema cell proliferation, and organization of limb primordia. ⺠A decrease in circulating ecdysteroid titer is also observed in injected animals. ⺠Hormone titers rise at late premolt, although injected animals fail to molt. ⺠RNAi can be an effective tool to dissect ecdysteroid-mediated signaling pathways.
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Authors
Sunetra Das, David S. Durica,