| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 10956220 | Molecular and Cellular Endocrinology | 2013 | 11 Pages |
Abstract
⺠Unlike in mammals, the AT2 of eel involves a classical cAMP signaling pathway. ⺠Eel AT2 is localized at spleen ellipsoid and straight arterioles. ⺠Selectivities of eel AT2 towards Ang II, Ang III, and Ang IV were identified. ⺠AT2/cAMP signaling was demonstrated in spleen primary culture. ⺠Various aspects of AT2s between teleosts and mammals were compared.
Keywords
PP2Aethyl 3-aminobenzoate methanesulfonateKT5823ATIPODQAT2SEAPSHP-1PKCCRERASMS-222GPCRpKaHEK2931H-[1,2,4]oxadiazolo[4,3-a]quinoxalin-1-oneG-protein coupled receptorPTpaseSecreted alkaline phosphatasedigoxigeninhuman embryonic kidney cell line 293Renin angiotensin systemcAMP signalingDIGSpleencAMP-responsive elementTeleostLigand affinityProtein tyrosine phosphataseprotein phosphatase 2protein kinase AProtein kinase Cguanylyl cyclaseangiotensin receptor
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Authors
Marty Kwok-Shing Wong, Yoshio Takei,