Article ID Journal Published Year Pages File Type
10956231 Molecular and Cellular Endocrinology 2012 11 Pages PDF
Abstract
► The melanocortin system is active during inflammation. ► Melanocortin peptides may induce extracellular matrix changes by mesenchymal progenitors. ► ACTH increases collagen synthesis by mesenchymal progenitors. ► Macrophage and mesenchymal cells are relevant sources of local melanocortin peptides. ► Functional melanocortin-2 receptors are expressed by aorta-derived mesenchymal progenitors.
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