| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 10956253 | Molecular and Cellular Endocrinology | 2012 | 15 Pages |
Abstract
⺠Enhanced at Puberty 1 (EAP1) is an upper-echelon transcriptional regulator of puberty and reproductive function. ⺠Transcription of EAP1 mRNA is initiated at a preferred Transcription Start Site. ⺠The EAP1 promoter is activated by two transcription factors, TTF1 and CUX1-p200. ⺠The EAP1 promoter is repressed by EAP1 itself, YY1 and CUX1-p110. ⺠All four transcription factors are recruited in vivo to the EAP1 promoter.
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Authors
Johanna K. Mueller, Ines Koch, Alejandro Lomniczi, Alberto Loche, Tomke Rulfs, Juan M. Castellano, Wieland Kiess, Sergio Ojeda, Sabine Heger,