| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 10956257 | Molecular and Cellular Endocrinology | 2012 | 12 Pages |
Abstract
⺠ER alpha and ER beta selective agonists reduce visceral fat mass. ⺠Effects of E2 on serum lipids are predominantly mediated via the ER alpha. ⺠Dietary genistein does not affect visceral fat mass and blood lipids. ⺠ER beta selective agonists modulate soleus muscle mRNA expression of Igf1 and Pax7. ⺠ER beta selective agonists possess anabolic activity.
Keywords
Pax7SERMVLDLHDLovariectomizedOVXERKO17β-estradiolIgf1AlphaBETApaired box 7World Health Organizationbody mass indexBMISkeletal muscleinsulin-like growth factor 1high-density lipoprotein cholesterolLDLGenisteinLipid metabolismSelective estrogen receptor modulatorObesityhigh fatGENtotal cholesterolVery-low-density lipoprotein cholesterolLow-density lipoprotein cholesterolLow fatWHOEstrogen receptorEstrogen receptor beta
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Authors
Carmen Weigt, Torsten Hertrampf, Nora Zoth, Karl Heinrich Fritzemeier, Patrick Diel,