Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
10956268 | Molecular and Cellular Endocrinology | 2012 | 5 Pages |
Abstract
⺠C-peptide induces human renal mesangial cell proliferation. ⺠Activation of PI-3 kinase and MAP kinase signaling pathway are involved in this process. ⺠C-peptide induces cyclin D1 expression and phosphorylation of retinoblastoma protein.
Keywords
DAPIPDGFPP2LY294002CDK4PD980594′,6-diamidino-2-phenylindolec-PeptideERK1/2extracellular-signal-regulated kinasesPI-3 kinaseMesangial cell proliferationmesangial cellsplatelet derived growth factorPhosphatidylinositol 3-kinaseDiabetic nephropathyretinoblastoma proteinprotein phosphatase 2cyclin-dependent kinase 4
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Authors
Dusica Vasic, Andreas Spyrantis, Renate Durst, Helga Bach, Sonja Vogt, Wolfgang Rottbauer, Daniel Walcher,