Article ID Journal Published Year Pages File Type
10956281 Molecular and Cellular Endocrinology 2012 11 Pages PDF
Abstract
► Gastrin 17 dose-dependently increase NO production in coronary endothelial cells. ► Both CCK1 and CCK2 subtypes receptors are involved in gastrin 17 effects. ► PKA and, slightly, PKC are the downstream effectors of CCK receptors activation. ► eNOS activation by gastrin 17 is dependent on ERK, Akt and p38 phosphorylation.
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Life Sciences Biochemistry, Genetics and Molecular Biology Cell Biology
Preview
CCK receptors-related signaling involved in nitric oxide production caused by gastrin 17 in porcine coronary endothelial cells
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