Article ID Journal Published Year Pages File Type
10956285 Molecular and Cellular Endocrinology 2012 11 Pages PDF
Abstract
► Both estradiol and testosterone can stimulate TCam-2 seminoma cell proliferation. ► Estradiol can activate GPER-cAMP/PKA signaling pathway. ► TCam-2 cells can express ERα36, a truncated isoform of the ERα receptor. ► ERα36 expression is rapidly induced after estrogen treatment in a GPER-dependent manner. ► ERα36 is required for estradiol-dependent EGFR expression.
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