| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 10956288 | Molecular and Cellular Endocrinology | 2012 | 12 Pages |
Abstract
⺠RNF20 (hBRE1A)/RNF40 (hBRE1B) complex monoubiquitylates histone H2B. ⺠mRNA expression data suggest that the RNF20 is deregulated in prostate cancers. ⺠RNF20 and RNF40 interact with androgen receptor. ⺠Depletion of RNF20/RNF40 retards the proliferation of LNCaP prostate cancer cells. ⺠Cellular amount of RNF20/RNF40 may contribute to the prostate cancer cell growth.
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Authors
Tiina Jääskeläinen, Harri Makkonen, Tapio Visakorpi, Jaehoon Kim, Robert G. Roeder, Jorma J. Palvimo,