Article ID Journal Published Year Pages File Type
10956291 Molecular and Cellular Endocrinology 2012 7 Pages PDF
Abstract
► SLC26A4 mRNA expression was evaluated in NaI-treated rats and PCCl3 cells. ► NaI treatment was carried out for 30 min up to 48 h. ► NaI treatment increased SLC26A4 mRNA content in both experimental models. ► Actinomycin D blocked this effect in PCCl3 cells. ► Iodide rapidly upregulates SLC26A4 mRNA expression by transcriptional mechanisms.
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Life Sciences Biochemistry, Genetics and Molecular Biology Cell Biology
Preview
Iodide treatment acutely increases pendrin (SLC26A4) mRNA expression in the rat thyroid and the PCCl3 thyroid cell line by transcriptional mechanisms
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