| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 10956292 | Molecular and Cellular Endocrinology | 2012 | 11 Pages |
Abstract
⺠The expression of cyp19a1b in the hypothalamus and pituitary of ricefield eel is not responsive to estrogens. ⺠The expression of cyp19a1b of ricefield eel in the pituitary is up-regulated by androgens. ⺠The expression of cyp19a1b in the brain and pituitary of ricefield eel is driven by alternative tissue-specific promoters. ⺠The brain-specific promoter of cyp19a1b contains a non-consensus ERE, thus does not respond to estrogen stimulation. ⺠The pituitary-specific promoter of cyp19a1b contains an ARE, which mediates the up-regulation by androgens.
Related Topics
Life Sciences
Biochemistry, Genetics and Molecular Biology
Cell Biology
Authors
Yang Zhang, Shen Zhang, Wenliang Zhou, Xing Ye, Wei Ge, Christopher H.K. Cheng, Haoran Lin, Weimin Zhang, Lihong Zhang,